Plague Inc.’s Bio-Weapon plague type poses a unique challenge when compared to its siblings. Its closest comparison is the Nano-Virus, in that its key challenge isn’t flying under the radar but managing its unique traits.
In this case it’s the Bio-Weapon’s lethality, which gradually increases over time. You want to keep this as low as possible until the world is completely infected, then kick it into overdrive. We’re going to provide you with tips and tricks on how to do just that in this guide.
What is the Bio-Weapon?
A Bio-Weapon is a man-made virus that functions very much like a typical virus except for the fact that you are in complete control of how it functions. In Plague Inc. it’s a plague type that is accidentally released from a laboratory, and gradually increases in lethality over time, which poses unique challenges.
The more lethal a plague is, the faster humanity aims to discover a cure but you’re also at risk of countries shutting their borders completely, which can hamper your chances of infecting the entire planet.
Fortunately, you do have a unique trick up your sleeve with the Bio-Weapon, and that’s in its special abilities. Here’s how each of these work:
As you can probably tell at this point, your first priority when playing this mode is in balancing growing your infectivity rate while also grabbing Gene Compression. We’ll go into full details later in this guide when we reach our full walkthrough.
How Does Bio-Weapon Differ in Terms of Gameplay?
Now that you understand how Bio-Weapon works, let’s take a look at how it differs in terms of gameplay. As we mentioned earlier, it’s very similar to Nano-Virus in that it has its own unique trait: lethality gradually increases over time. This puts pressure on you to infect the planet quickly, before countries start closing their borders.
So it suits a faster-paced gameplay style for those that like to think on their feet. You’ll spend your early game simultaneously managing the lethality while increasing infectivity. Once you’ve infected the entire planet, you can end the game incredibly quickly thanks to the special skill Unlock Annihilate Gene, which will have humanity on its knees in a matter of days.
While we’re not going to cover a speed run in this guide, this plague type is ideal for speed runners as the rate at which you can wipe out humanity is absolutely insane. It does require very careful management though, so you will have to be organised.
Bio-Weapon Normal Strategy
Bio-Weapon took us a good few goes to get right. The key challenge is managing that lethality, which starts to spike really early on, and has countries shutting their borders quickly. You’ll also find that humanity focuses on a cure rate a lot faster than normal, and progress can spike almost as fast as lethality if you don’t manage it.
However, we have settled on a strategy that worked for us every single time. We’ll give you a rundown of the general things you should be working on at each moment, but you will need to think on the fly, as this type of plague in particular takes on a bit of a life of its own.
